Rankings Pharma & medtech Sanofi

Sanofi

Pharma & medtech · FranceRank 137 of 829Prices 3 Nov 2026Model 1.4

A strong score: the model found few serious problems, but analysts see limited upside from here.

Biggest deductions

  • Product concentration−8
  • Execution (late-stage pipeline)−7
  • Future pipeline−3

Strengths

  • Estimates+2
  • Dividend and buybacks from FCF+2
  • New launches+2

How the score is built

From 100 to 79, step by step: points off for the business, the price and the cracks, back for documented strengths, then three data adjustments.

100Start
79Score

Hover or select a step to see what drove it. Steps with findings open them below.

Key numbers

As of 3 Nov 2026. Analyst targets tend to be optimistic; read upside as a hint, not a forecast.

Price
81.51 EUR
Median analyst target
95.00 EUR
Upside to median
+16.6%
Analysts
25
Target range
78.00 – 107.20 EUR
52-week change
−7%
P/E (trailing)
23.6
Forward P/E
8.8
PEG
1.05

Findings

Every deduction and every plus, with its source. Open a step to read them.

Business

Is the company getting stronger, not just bigger? · 3 findings
−7 of −30
  • ROIC
    ROIC has been 8.1–10.2% in 2021–25 and is 9.1% TTM; ROE is only 5.7%. A modest return for a big pharma group.
    −2
  • Quality of growth
    Dupixent grew 37.6% to €5.2bn in Q2 and carries most of the group's 17.8% growth, while vaccines fell 4.7%.
    −2
  • Future pipeline
    The chief scientific officer calls the number of first-in-human starts 'abysmal'. The early pipeline must be rebuilt, and half of innovation will now be bought in, including late-stage assets (acquisitions of €10.2bn TTM).
    −3

Price

Today's multiples against the company's own history and its peers. · 1 finding
−2 of −35
  • Multiples vs own history and peers
    Forward P/E 8.2 vs 10.0–12.5 in 2021–25; EV/EBITDA 7.7 vs 9.0–11.5; P/FCF 8.6 vs 11.2–15.9; dividend yield 5.7%. Below the bottom of its own range, but the discount reflects the patent expiry in 2031.
    −2

Cracks

Cash flow, customers, debt, insiders, guidance and what sits behind the headline numbers. · 5 findings
−22 of −35
  • Product concentration
    Dupixent was €5.2bn of €11.6bn (45%) of Q2 sales; the US compound patent expires in 2031.
    −8
  • Execution (late-stage pipeline)
    Amlitelimab will not be filed globally (impairment of €952m), itepekimab, balinatunfib and belantamab have been stopped, and the FDA rejected tolebrutinib, citing a risk of serious liver injury and unclear efficacy.
    −7
  • Governance and management change
    The CEO's contract was not renewed, the executive team was reorganised (July), and a new head of R&D started in September. He is now reviewing more phase 2 and 3 programmes.
    −2
  • Vaccines
    Vaccine sales fell 4.7% to €1.1bn in Q2 (influenza); TTM they are €7.8bn vs €8.3bn in 2024.
    −2
  • Macro
    Political pressure on US drug prices (IRA negotiations and MFN policy) hits the US, the largest market.
    −3

Plus

Only documented strengths. · 4 findings
+7 of +15
  • Estimates
    2026 guidance raised to about 10% sales growth, with business EPS growing slightly faster than sales.
    +2
  • Dividend and buybacks from FCF
    Dividends (€4.9bn) and buybacks (€2.0bn) on a TTM basis are below FCF of €10.0bn; the €1bn buyback is completed, and the share count has fallen 2.5%.
    +2
  • New launches
    Pharma launches (Ayvakit, ALTUVIIIO, Sarclisa and others) grew 48.3% to €1.3bn in Q2.
    +2
  • Diversified base
    A geographically spread business with seven regulatory approvals in H1, but the dependence on Dupixent weighs.
    +1

Caveats

What the score does not capture, or where the data is weak.
Dupixent was 45% of sales in Q2, and the US compound patent expires in 2031. New management and a new head of R&D are reviewing the late-stage pipeline, so several projects may be stopped. IFRS EPS (€0.29 in Q2) is far below business EPS (€2.09) because of impairments. Whether Dupixent is exposed to IRA price negotiations has not been examined. Q3 results 30/10.

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